THC, CBD and Huntington’s

Huntington’s is the result of a genetic defect.  The defect causes a portion of the DNA to repeat more times than is normal. The affected cells are located in the brain. Huntington’s is inherited. As it’s passed down from generation to generation the onset begins at earlier ages. There is no known cure. Death normally occurs around 15 to 20 years after onset — unless the affected individual takes their life, which is common.

The abstract I’ll link to almost reads like an advertisement for GW Pharmaceuticals Sativex. That’s okay. I mean, even if it was an ad for Bayer I’d be good with it. Oh, wait… Bayer is marketing Sativex in Canada, huh?

I find a couple of things exciting about this preclinical study, and one interesting.

The exciting parts are that Sativex is not a synthetic. Sativex is a phytocannabinoid extract. The other, obviously, is that a 1:1 ratio of THC and CBD appear to delay the progression of the disease. Good stuff there, man!

The interesting part is that even when the CB1 and CB2 (endocannabinoid) receptors are blocked with an antagonist, it still works. Something else must be going on in there, eh? The study suggests the possibility of some sort of antioxidant properties.

Here’s your link:
Huntington’s

I don’t want to go off on a tirade, but… When the Hell is the U.S. (and other governments) going to admit that keeping cannabis in schedule I is costing human lives? Fine, don’t admit it, just pull the damn plant from I already! People are needlessly dying!

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